Open AccessAge-Related Conjunctival Disease in the C57BL/6.NOD-Aec1Aec2Mouse Model of Sjögren Syndrome Develops Independent of Lacrimal Dysfunction
Author(s) -
In Cheon You,
Fang Bian,
Eugene A. Volpe,
Cintia S. de Paiva,
Stephen C. Pflugfelder
Publication year - 2015
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.14-15668
Subject(s) - conjunctiva , goblet cell , pathology , cd8 , flow cytometry , infiltration (hvac) , cytokine , histology , medicine , immunohistochemistry , cd68 , biology , immunology , immune system , epithelium , physics , thermodynamics
To investigate parameters of ocular surface disease in C57BL/6.NOD-Aec1Aec2 (Aec) mice with aging and their correlation with development of Sjögren syndrome (SS)-like lacrimal gland (LG) disease.