Age-Related Conjunctival Disease in the C57BL/6.NOD-Aec1Aec2Mouse Model of Sjögren Syndrome Develops Independent of Lacrimal Dysfunction | Zendy

In Cheon You | Zendy; Fang Bian | Zendy; Eugene A. Volpe | Zendy; Cintia S. de Paiva | Zendy; Stephen C. Pflugfelder | Zendy

Open Access

Age-Related Conjunctival Disease in the C57BL/6.NOD-Aec1Aec2Mouse Model of Sjögren Syndrome Develops Independent of Lacrimal Dysfunction

Author(s) -

In Cheon You,

Fang Bian,

Eugene A. Volpe,

Cintia S. de Paiva,

Stephen C. Pflugfelder

Publication year - 2015

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.14-15668

Subject(s) - conjunctiva , goblet cell , pathology , cd8 , flow cytometry , infiltration (hvac) , cytokine , histology , medicine , immunohistochemistry , cd68 , biology , immunology , immune system , epithelium , physics , thermodynamics

To investigate parameters of ocular surface disease in C57BL/6.NOD-Aec1Aec2 (Aec) mice with aging and their correlation with development of Sjögren syndrome (SS)-like lacrimal gland (LG) disease.

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