Open AccessDegeneration and Regeneration of Corneal Nerves in Response to HSV-1 Infection
Author(s) -
Ana J. ChucairElliott,
Min Zheng,
Daniel J.J. Carr
Publication year - 2015
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.14-15596
Subject(s) - cornea , reinnervation , immunohistochemistry , medicine , neurofilament , keratitis , ophthalmology , pathology , biology , anatomy
Herpes simplex virus type 1 (HSV-1) infection is one cause of neurotrophic keratitis, characterized by decreases in corneal sensation, blink reflex, and tear secretion as consequence of damage to the sensory fibers innervating the cornea. Our aim was to characterize changes in the corneal nerve network and its function in response to HSV-1 infection.
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