Open AccessActivation of TLR3 Promotes the Degeneration of Retinal Ganglion Cells by Upregulating the Protein Levels of JNK3
Author(s) -
Shravan K. Chintala,
Nahrain Putris,
Mason Geno
Publication year - 2015
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.14-15539
Subject(s) - downregulation and upregulation , tlr3 , microbiology and biotechnology , retina , western blot , inner plexiform layer , biology , toll like receptor , retinal degeneration , chemistry , receptor , innate immune system , biochemistry , neuroscience , gene
To investigate whether activation of Toll-like receptor 3 (TLR3) promotes the degeneration of retinal ganglion cells (RGCs) by upregulating the protein levels of c-jun N-terminal kinase 3 (JNK3).
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