Exposure of a Corneal Epithelial Cell Line (hTCEpi) to Demodex-Associated Bacillus Proteins Results in an Inflammatory Response
Author(s) -
Fred McMahon,
Catherine Gallagher,
Niall J. O’Reilly,
Martin Clynes,
Finbarr O’Sullivan,
Kevin Kavanagh
Publication year - 2014
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.14-15018
Subject(s) - demodex , microbiology and biotechnology , inflammatory response , biology , line (geometry) , immunology , inflammation , botany , geometry , mathematics , mite
A role for a bacterium, Bacillus oleronius, originally isolated from a Demodex mite, in the induction of ocular rosacea has been proposed. The aim of this work was to characterize the response of a corneal epithelial cell line to Bacillus proteins, as this might give an insight into how such proteins contribute to the symptoms of ocular rosacea in vivo.
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