Design and Characterization of an Ocular Topical Liposomal Preparation to Replenish the Lipids of the Tear Film | Zendy

Marta VicariodelaTorre | Zendy; J.M. Benítez-del-Castillo | Zendy; Eva Aladro Vico | Zendy; M. Guzmán | Zendy; Beatriz de las Heras | Zendy; Rocío HerreroVanrell | Zendy; Irene T. MolinaMartínez | Zendy

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Design and Characterization of an Ocular Topical Liposomal Preparation to Replenish the Lipids of the Tear Film

Author(s) -

Marta VicariodelaTorre,

J.M. Benítez-del-Castillo,

Eva Aladro Vico,

M. Guzmán,

Beatriz de las Heras,

Rocío HerreroVanrell,

Irene T. MolinaMartínez

Publication year - 2014

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.14-14700

Subject(s) - liposome , in vivo , bioadhesive , chemistry , phosphatidylcholine , chromatography , osmotic concentration , pharmacology , ophthalmology , medicine , drug delivery , biochemistry , organic chemistry , membrane , biology , phospholipid , microbiology and biotechnology

Dry eye (DE) includes a group of diseases related to tear film disorders. Current trends for DE therapy focus on providing lipid components to replace the damaged lipid layer. Formulations that contain aqueous and mucin-like compounds may have additional therapeutic benefits for DE patients. The aim of this work was to design and evaluate novel formulations having the potential to become topical treatment for DE.

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