Pharmacologic Alternatives to Riboflavin Photochemical Corneal Cross-Linking: A Comparison Study of Cell Toxicity Thresholds | Zendy

Mijung Kim | Zendy; Anna Takaoka | Zendy; Quan V. Hoang | Zendy; Stephen L. Trokel | Zendy; David C. Paik | Zendy

Open Access

Pharmacologic Alternatives to Riboflavin Photochemical Corneal Cross-Linking: A Comparison Study of Cell Toxicity Thresholds

Author(s) -

Mijung Kim,

Anna Takaoka,

Quan V. Hoang,

Stephen L. Trokel,

David C. Paik

Publication year - 2014

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.13-13703

Subject(s) - toxicity , trypan blue , cell culture , benzalkonium chloride , cornea , chemistry , cell , biochemistry , pharmacology , biology , chromatography , genetics , organic chemistry , neuroscience

The efficacy of therapeutic cross-linking of the cornea using riboflavin photochemistry (commonly abbreviated as CXL) has caused its use to become widespread. Because there are known chemical agents that cross-link collagenous tissues, it may be possible to cross-link tissue pharmacologically. The present study was undertaken to compare the cell toxicity of such agents.

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