Decreased Proteasomal Activity Causes Photoreceptor Degeneration in Mice
Author(s) -
Ryõ Andõ,
Kousuke Noda,
Utano Tomaru,
Mamoru Kamoshita,
Yoko Ozawa,
Shoji Notomi,
Toshio Hisatomi,
Mika Noda,
Atsuhiro Kanda,
Tatsuro Ishibashi,
Masanori Kasahara,
Susumu Ishida
Publication year - 2014
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.13-13272
Subject(s) - outer nuclear layer , retinal degeneration , tunel assay , apoptosis , retinal , photoreceptor cell , inner nuclear layer , erg , chemistry , retina , retinitis pigmentosa , photopic vision , electroretinography , endocrinology , medicine , microbiology and biotechnology , biology , biochemistry , neuroscience
To study the retinal degeneration caused by decreased proteasomal activity in β5t transgenic (β5t-Tg) mice, an animal model of senescence acceleration.
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