Enzymatic Degradation Identifies Components Responsible for the Structural Properties of the Vitreous Body | Zendy

Benjamen A. Filas | Zendy; Qianru Zhang | Zendy; Ruth J. Okamoto | Zendy; YingBo Shui | Zendy; David C. Beebe | Zendy

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Enzymatic Degradation Identifies Components Responsible for the Structural Properties of the Vitreous Body

Author(s) -

Benjamen A. Filas,

Qianru Zhang,

Ruth J. Okamoto,

YingBo Shui,

David C. Beebe

Publication year - 2013

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.13-13026

Subject(s) - hyaluronidase , chemistry , biophysics , collagenase , biochemistry , enzyme , biology

Vitreous degeneration contributes to several age-related eye diseases, including retinal detachment, macular hole, macular traction syndrome, and nuclear cataracts. Remarkably little is understood about the molecular interactions responsible for maintaining vitreous structure. The purpose of this study was to measure the structural properties of the vitreous body after enzymatic degradation of selected macromolecules.

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