Open AccessAn Investigative Peptide–Acyclovir Combination to Control Herpes Simplex Virus Type 1 Ocular Infection
Author(s) -
Paul J. Park,
Thessicar E. Antoine,
Asim V. Farooq,
Tibor Vályi-Nagy,
Deepak Shukla
Publication year - 2013
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.13-12832
Subject(s) - herpes simplex virus , ex vivo , in vivo , virology , immunohistochemistry , western blot , in vitro , antiviral drug , virus , peptide , medicine , pharmacology , biology , immunology , biochemistry , microbiology and biotechnology , gene
To investigate the efficacy of a combination treatment composed of the cationic, membrane-penetrating peptide G2, and acyclovir (ACV) in both in vitro and ex vivo models of herpes simplex virus 1 (HSV-1) ocular infection.