Open AccessSigma Receptor Ligand, (+)-Pentazocine, Suppresses Inflammatory Responses of Retinal Microglia
Author(s) -
Jing Zhao,
Yonju Ha,
Gregory I. Liou,
Graydon B. Gonsalvez,
Sylvia B. Smith,
Kathryn Bollinger
Publication year - 2014
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.13-12823
Subject(s) - pentazocine , microglia , tumor necrosis factor alpha , chemistry , viability assay , lipopolysaccharide , microbiology and biotechnology , pharmacology , endocrinology , biology , medicine , inflammation , biochemistry , cell , morphine
To evaluate the effects of the σ 1 receptor (σR1) agonist, (+)-pentazocine, on lipopolysaccharide (LPS)-induced inflammatory changes in retinal microglia cells.
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