MicroRNA Signature in Wound Healing Following Excimer Laser Ablation: Role of miR-133b on TGFβ1, CTGF, SMA, and COL1A1 Expression Levels in Rabbit Corneal Fibroblasts | Zendy

Paulette M. Robinson | Zendy; TsaiDer Chuang | Zendy; Sriniwas Sriram | Zendy; Liya Pi | Zendy; Xiao Luo | Zendy; Bryon E. Petersen | Zendy; Gregory S. Schultz | Zendy

Open Access

MicroRNA Signature in Wound Healing Following Excimer Laser Ablation: Role of miR-133b on TGFβ1, CTGF, SMA, and COL1A1 Expression Levels in Rabbit Corneal Fibroblasts

Author(s) -

Paulette M. Robinson,

TsaiDer Chuang,

Sriniwas Sriram,

Liya Pi,

Xiao Luo,

Bryon E. Petersen,

Gregory S. Schultz

Publication year - 2013

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.13-12621

Subject(s) - ctgf , connective tissue , wound healing , growth factor , microrna , transforming growth factor , biology , microbiology and biotechnology , chemistry , andrology , immunology , medicine , gene , biochemistry , genetics , receptor

The role of microRNA (miRNA) regulation in corneal wound healing and scar formation has yet to be elucidated. This study analyzed the miRNA expression pattern involved in corneal wound healing and focused on the effect of miR-133b on expression of several profibrotic genes.

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