Open AccessThe Effects of Age on Lens Transport
Author(s) -
Junyuan Gao,
Huan Wang,
Xiaoyan Sun,
K. Varadaraj,
Le-ping Li,
Thomas W. White,
Richard T. Mathias
Publication year - 2013
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.13-12593
Subject(s) - intracellular , extracellular , biophysics , gap junction , chemistry , calcium in biology , connexin , hydrostatic pressure , biology , biochemistry , physics , thermodynamics
Age-related nuclear cataracts involve denaturation and aggregation of intracellular proteins. We have documented age-dependent changes in membrane transport in the mouse lens to see what might initiate changes in the intracellular milieu.