Functional Principal Component Analysis Reveals Discriminating Categories of Retinal Pigment Epithelial Morphology in Mice
Author(s) -
Yi Jiang,
Xin Qi,
Micah A Chrenek,
Christopher Gardner,
Jeffrey H. Boatright,
Hans E. Grossniklaus,
John M. Nickerson
Publication year - 2013
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.13-12450
Subject(s) - morphology (biology) , retinal , phenotype , retinal pigment epithelium , biology , retina , anatomy , principal component analysis , cell type , pathology , cell , ophthalmology , medicine , genetics , neuroscience , biochemistry , gene , artificial intelligence , computer science
To determine whether multivariate, functional principal component analysis of the size and shape of retinal pigment epithelial (RPE) cell morphology allows discrimination of mouse RPE genotypes and age.
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