Open AccessOptical Coherence Tomography Study of Experimental Anterior Ischemic Optic Neuropathy and Histologic Confirmation
Author(s) -
Joyce K. Ho,
Madison Stanford,
Mohammad Ali Shariati,
Roopa Dalal,
Yaping Joyce Liao
Publication year - 2013
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.13-12419
Subject(s) - optical coherence tomography , medicine , anterior ischemic optic neuropathy , ophthalmology , optic nerve
The optic nerve is part of the central nervous system, and interruption of this pathway due to ischemia typically results in optic atrophy and loss of retinal ganglion cells. In this study, we assessed in vivo retinal changes following murine anterior ischemic optic neuropathy (AION) by using spectral-domain optical coherence tomography (SD-OCT) and compared these anatomic measurements to that of histology.