Open AccessTear Cytokine Profile as a Noninvasive Biomarker of Inflammation for Ocular Surface Diseases: Standard Operating Procedures
Author(s) -
Yi Wei,
Neha Gadaria-Rathod,
Seth Epstein,
Penny A. Asbell
Publication year - 2013
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.13-12132
Subject(s) - medicine , cytokine , biomarker , tears , clinical trial , multiplex , immunology , pathology , bioinformatics , biology , biochemistry
To provide standard operating procedures (SOPs) for measuring tear inflammatory cytokine concentrations and to validate the resulting profile as a minimally invasive objective metric and biomarker of ocular surface inflammation for use in multicenter clinical trials on dry eye disease (DED).