Open AccessRetinoic Acid Inhibits CD25+Dendritic Cell Expansion and γδ T-Cell Activation in Experimental Autoimmune Uveitis
Author(s) -
Dongchun Liang,
Aijun Zuo,
Hui Shao,
Willi K. Born,
Rebecca L. O’Brien,
Henry J. Kaplan,
Deming Sun
Publication year - 2013
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.12-11432
Subject(s) - il 2 receptor , t cell , immunology , retinoic acid , interleukin 21 , chemistry , microbiology and biotechnology , cancer research , biology , immune system , biochemistry , gene
We determined the mechanism by which all-trans retinoic acid (ATRA) inhibits experimental autoimmune uveitis (EAU) and determined the role of γδ T cells in this autoimmune disease.