Fluid Circulation Determined in the Isolated Bovine Lens | Zendy

Oscar A. Candia | Zendy; Richard T. Mathias | Zendy; Rosana Gerometta | Zendy

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Fluid Circulation Determined in the Isolated Bovine Lens

Author(s) -

Oscar A. Candia,

Richard T. Mathias,

Rosana Gerometta

Publication year - 2012

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.12-10295

Subject(s) - ouabain , capillary action , lens (geology) , chemistry , circulation (fluid dynamics) , equator , open circuit voltage , mechanics , biophysics , sodium , optics , physics , thermodynamics , biology , latitude , organic chemistry , quantum mechanics , astronomy , voltage

In 1997, a theoretical model was developed that predicted the existence of an internal, Na(+)-driven fluid circulation from the poles to the equator of the lens. In the present work, we demonstrate with a novel system that fluid movement can be measured across the polar and equatorial surface areas of isolated cow lenses. We have also determined the effects of ouabain and reduced bath [Na(+)].

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