A Microparticle/Hydrogel Combination Drug-Delivery System for Sustained Release of Retinoids | Zendy

Song-Qi Gao | Zendy; Tadao Maeda | Zendy; Kiichiro Okano | Zendy; Krzysztof Palczewski | Zendy

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A Microparticle/Hydrogel Combination Drug-Delivery System for Sustained Release of Retinoids

Author(s) -

Song-Qi Gao,

Tadao Maeda,

Kiichiro Okano,

Krzysztof Palczewski

Publication year - 2012

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.12-10279

Subject(s) - microparticle , drug delivery , pharmacology , drug , in vivo , chemistry , retinal , electroretinography , subcutaneous injection , medicine , ophthalmology , biology , microbiology and biotechnology , organic chemistry , astrobiology

To design and develop a drug-delivery system containing a combination of poly(D,L-lactide-co-glycolide) (PLGA) microparticles and alginate hydrogel for sustained release of retinoids to treat retinal blinding diseases that result from an inadequate supply of retinol and generation of 11-cis-retinal.

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