Innate Immune Regulation ofSerratia marcescens–Induced Corneal Inflammation and Infection
Author(s) -
Rong Zhou,
Rui Zhang,
Yan Sun,
Sean Platt,
Loretta SzczotkaFlynn,
Eric Pearlman
Publication year - 2012
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.12-10238
Subject(s) - serratia marcescens , innate immune system , inflammation , immunology , microbiology and biotechnology , immune system , medicine , biology , escherichia coli , biochemistry , gene
Serratia marcescens is frequently isolated from lenses of patients with contact lens-associated corneal infiltrates. In the current study, we examined the role of toll-like receptors (TLRs) and interleukin-1 receptor type 1 (IL-1R1) in S. marcescens-induced corneal inflammation and infection.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom