RPGR-Associated Retinal Degeneration in Human X-Linked RP and a Murine Model
Author(s) -
Wei Huang,
Alan F. Wright,
Alejandro J. Román,
Artur V. Cideciyan,
Forbes D.C. Manson,
Dina Y. Gewaily,
Sharon Schwartz,
Sam Sadigh,
Maria P. Limberis,
Peter Bell,
James M. Wilson,
Anand Swaroop,
Samuel G. Jacobson
Publication year - 2012
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.12-10070
Subject(s) - electroretinography , retinitis pigmentosa , retinal degeneration , retinal , retina , biology , retinopathy , erg , ophthalmology , pathology , medicine , neuroscience , endocrinology , diabetes mellitus
We investigated the retinal disease due to mutations in the retinitis pigmentosa GTPase regulator (RPGR) gene in human patients and in an Rpgr conditional knockout (cko) mouse model.
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