Anti-Inflammatory Effects of Lutein in Retinal Ischemic/Hypoxic Injury: In Vivo and In Vitro Studies | Zendy

Suk-Yee Li | Zendy; Frederic K. C. Fung | Zendy; Zhongjie Fu | Zendy; David Wong | Zendy; Henry Holung Chan | Zendy; Acy Lo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Anti-Inflammatory Effects of Lutein in Retinal Ischemic/Hypoxic Injury: In Vivo and In Vitro Studies

Author(s) -

Suk-Yee Li,

Frederic K. C. Fung,

Zhongjie Fu,

David Wong,

Henry Holung Chan,

Acy Lo

Publication year - 2012

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.12-10007

Subject(s) - lutein , retinal , glial fibrillary acidic protein , reperfusion injury , inflammation , gliosis , retina , microglia , electroretinography , chemistry , ischemia , endocrinology , biology , pharmacology , immunology , medicine , pathology , biochemistry , neuroscience , immunohistochemistry , carotenoid

Lutein protects retinal neurons by its anti-oxidative and anti-apoptotic properties in ischemia/reperfusion (I/R) injury while its anti-inflammatory effects remain unknown. As Müller cells play a critical role in retinal inflammation, the effect of lutein on Müller cells was investigated in a murine model of I/R injury and a culture model of hypoxic damage.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research