Heparanase and Vascular Endothelial Growth Factor Expression Is Increased in Hypoxia-Induced Retinal Neovascularization
Author(s) -
Jie Hu,
Xin Song,
Yi He,
Craig Freeman,
Christopher R. Parish,
Ling Yuan,
Honghua Yu,
Shibo Tang
Publication year - 2012
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-9144
Subject(s) - heparanase , retinal , western blot , hypoxia (environmental) , vascular endothelial growth factor , neovascularization , angiogenesis , retina , vascular endothelial growth factor a , chemistry , microbiology and biotechnology , endocrinology , medicine , biology , vegf receptors , biochemistry , oxygen , cancer , organic chemistry , neuroscience , gene , metastasis
Heparanase and VEGF are related closely to angiogenesis in cancer. The purpose of our study was to evaluate the expression and correlation of heparanase and VEGF in hypoxia-induced retinal neovascularization.
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