Spectral-Domain Optical Coherence Tomography as a Noninvasive Method to Assess Damaged and Regenerating Adult Zebrafish Retinas
Author(s) -
Travis J. Bailey,
Darin H. Davis,
Joseph E. Vance,
David R. Hyde
Publication year - 2012
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-8895
Subject(s) - zebrafish , optical coherence tomography , retina , retinal , histology , outer nuclear layer , anatomy , inner nuclear layer , retinal regeneration , biology , ophthalmology , biophysics , medicine , neuroscience , biochemistry , genetics , gene
These experiments assessed the ability of spectral-domain optical coherence tomography (SD-OCT) to accurately represent the structural organization of the adult zebrafish retina and reveal the dynamic morphologic changes during either light-induced damage and regeneration of photoreceptors or ouabain-induced inner retinal damage.
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