Compound 49b Prevents Diabetes-Induced Apoptosis through Increased IGFBP-3 Levels | Zendy

Qiuhua Zhang | Zendy; Kimberly Guy | Zendy; Jayaprakash Pagadala | Zendy; Youde Jiang | Zendy; Robert J. Walker | Zendy; Luhong Liu | Zendy; Carl Soderland | Zendy; Timothy S. Kern | Zendy; Robert J. Ferry | Zendy; Hui He | Zendy; Charles R. Yates | Zendy; Duane D. Miller | Zendy; Jena J. Steinle | Zendy

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Compound 49b Prevents Diabetes-Induced Apoptosis through Increased IGFBP-3 Levels

Author(s) -

Qiuhua Zhang,

Kimberly Guy,

Jayaprakash Pagadala,

Youde Jiang,

Robert J. Walker,

Luhong Liu,

Carl Soderland,

Timothy S. Kern,

Robert J. Ferry,

Hui He,

Charles R. Yates,

Duane D. Miller,

Jena J. Steinle

Publication year - 2012

Publication title -

investigative ophthalmology and visual science

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.11-8779

Subject(s) - retinal , retina , pericyte , ganglion cell layer , endocrinology , apoptosis , medicine , biology , electroretinography , endothelial stem cell , in vitro , biochemistry , neuroscience

To determine whether Compound 49b, a novel PKA-activating drug, can prevent diabetic-like changes in the rat retina through increased insulin-like growth factor binding protein-3 (IGFBP-3) levels.

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