Prominin-1 Localizes to the Open Rims of Outer Segment Lamellae inXenopus laevisRod and Cone Photoreceptors
Author(s) -
Zhou Han,
David W. Anderson,
David S. Papermaster
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-8635
Subject(s) - xenopus , biology , peripherin , retina , microbiology and biotechnology , visual phototransduction , immunocytochemistry , opsin , outer nuclear layer , anatomy , retinal , gene , biochemistry , neuroscience , rhodopsin , endocrinology
Prominin-1 expresses in rod and cone photoreceptors. Mutations in the prominin-1 gene cause retinal degeneration in humans. In this study, the authors investigated the expression and subcellular localization of xlProminin-1 protein, the Xenopus laevis ortholog of prominin-1, in rod and cone photoreceptors of this frog.
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