Retinoid Content, Visual Responses, and Ocular Morphology Are Compromised in the Retinas of Mice Lacking the Retinol-Binding Protein Receptor, STRA6 | Zendy

Alberto Ruíz | Zendy; Manuel Mark | Zendy; Hugues Jacobs | Zendy; Muriel Klopfenstein | Zendy; Jane Hu | Zendy; Marcia Lloyd | Zendy; Samer Habib | Zendy; Chinatsu Tosha | Zendy; Roxana A. Radu | Zendy; Norbert B. Ghyselinck | Zendy; Steven Nusinowitz | Zendy; Dean Bok | Zendy

Open Access

Retinoid Content, Visual Responses, and Ocular Morphology Are Compromised in the Retinas of Mice Lacking the Retinol-Binding Protein Receptor, STRA6

Author(s) -

Alberto Ruíz,

Manuel Mark,

Hugues Jacobs,

Muriel Klopfenstein,

Jane Hu,

Marcia Lloyd,

Samer Habib,

Chinatsu Tosha,

Roxana A. Radu,

Norbert B. Ghyselinck,

Steven Nusinowitz,

Dean Bok

Publication year - 2012

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.11-8476

Subject(s) - retina , retinoid , biology , retinol , immunocytochemistry , endocrinology , retinal , medicine , chemistry , retinoic acid , biochemistry , cell culture , neuroscience , vitamin , genetics

We report generation of a mouse model in which the STRA6 gene has been disrupted functionally to facilitate the study of visual responses, changes in ocular morphology, and retinoid processing under STRA6 protein deficiency.

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