Isolation and Expansion of Human Limbal Stromal Niche Cells | Zendy

Hua-Tao Xie | Zendy; SzuYu Chen | Zendy; Guigang Li | Zendy; Scheffer C.G. Tseng | Zendy

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Isolation and Expansion of Human Limbal Stromal Niche Cells

Author(s) -

Hua-Tao Xie,

SzuYu Chen,

Guigang Li,

Scheffer C.G. Tseng

Publication year - 2011

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.11-8441

Subject(s) - matrigel , dispase , fetal bovine serum , sox2 , biology , stromal cell , microbiology and biotechnology , homeobox protein nanog , trypsinization , stem cell , embryonic stem cell , mesenchymal stem cell , chemistry , collagenase , cell , induced pluripotent stem cell , cancer research , biochemistry , trypsin , gene , enzyme

Limbal stromal niche cells heterogeneously express embryonic stem cell (SC) markers. This study was conducted to isolate and expand them and to prove that their phenotype is critical for supporting SCs.

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