Open AccessAlterations in Protein Expression in Tree Shrew Sclera during Development of Lens-Induced Myopia and Recovery
Author(s) -
Michael R. Frost,
Thomas T. Norton
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-8354
Subject(s) - sclera , extracellular matrix , lens (geology) , fibronectin , biology , microbiology and biotechnology , ophthalmology , anatomy , chemistry , medicine , paleontology
During the development of, and recovery from, negative lens-induced myopia there is regulated remodeling of the scleral extracellular matrix (ECM) that controls the extensibility of the sclera. Difference gel electrophoresis (DIGE) was used to identify and categorize proteins whose levels are altered in this process.
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