Abnormal Achromatic and Chromatic Contrast Sensitivity in Neurofibromatosis Type 1
Author(s) -
Maria José Ribeiro,
Inês R. Violante,
Inês Bernardino,
Fabiana Ramos,
Jorge Saraiva,
Pablo Reviriego,
Meena Upadhyaya,
Eduardo Silva,
Miguel CasteloBranco
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-8225
Subject(s) - achromatic lens , parvocellular cell , contrast (vision) , chromatic scale , audiology , neurofibromatosis , spatial frequency , color vision , psychology , medicine , neuroscience , optics , pathology , physics , central nervous system
Neurofibromatosis type 1 (NF1) is a monogenic disorder with the majority of patients presenting subtle to moderate cognitive impairments. Visuospatial deficits are considered to be one of the hallmark characteristics of their cognitive profile. However, low-level visual processing has not been previously investigated. Our aim was to study contrast perception in these patients to assess the function of early visual areas.
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