Bicarbonate, NBCe1, NHE, and Carbonic Anhydrase Activity Enhance Lactate-H+Transport in Bovine Corneal Endothelium | Zendy

Tracy T. Nguyen | Zendy; Joseph A. Bonanno | Zendy

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Bicarbonate, NBCe1, NHE, and Carbonic Anhydrase Activity Enhance Lactate-H⁺Transport in Bovine Corneal Endothelium

Author(s) -

Tracy T. Nguyen,

Joseph A. Bonanno

Publication year - 2011

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.11-8086

Subject(s) - dids , niflumic acid , chemistry , symporter , amiloride , intracellular ph , acetazolamide , cotransporter , carbonic anhydrase , bumetanide , bicarbonate , apical membrane , carbonic anhydrase inhibitor , sodium , biochemistry , medicine , transporter , intracellular , enzyme , membrane , organic chemistry , gene

To identify and localize the monocarboxylate transporters (MCTs) expressed in bovine corneal endothelial cells (BCEC) and to test the hypothesis that buffering contributed by HCO(3)(-), sodium bicarbonate cotransporter (NBCe1), sodium hydrogen exchanger (NHE), and carbonic anhydrase (CA) activity facilitates lactate flux.

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