Analysis of the Role of ZEB1 in the Pathogenesis of Posterior Polymorphous Corneal Dystrophy
Author(s) -
Vivek S. Yellore,
Sylvia A. Rayner,
Catherine K. Nguyen,
Rajendra K. Gangalum,
Zhe Jing,
Suraj P. Bhat,
Anthony J. Aldave
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-8038
Subject(s) - biology , pathogenesis , cornea , gene , gene expression , transcription factor , microbiology and biotechnology , genetics , immunology , neuroscience
To determine how nonsense mutations in the transcription factor ZEB1 lead to the development of posterior polymorphous corneal dystrophy type 3 (PPCD3).
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