The Maintenance of Lymphatic Vessels in the Cornea Is Dependent on the Presence of Macrophages
Author(s) -
Kazuichi Maruyama,
Toru Nakazawa,
Claus Cursiefen,
Yuko Maruyama,
Nico van Rooijen,
Patricia A. D’Amore,
Shigeru Kinoshita
Publication year - 2012
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-8010
Subject(s) - lymphangiogenesis , lymphatic system , lymphatic vessel , lymphatic endothelium , cornea , pathology , integrin alpha m , transplantation , medicine , immune system , immunology , ophthalmology , surgery , cancer , metastasis
It has been shown previously that the presence in the cornea of antigen-presenting cells (APC), such as macrophages (MPS) and lymphangiogenesis, is a risk for corneal transplantation. We sought to determine whether the existence of lymphatic vessels in the non-inflamed cornea is associated with the presence of MPS.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom