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The Maintenance of Lymphatic Vessels in the Cornea Is Dependent on the Presence of Macrophages
Author(s) -
Kazuichi Maruyama,
Toru Nakazawa,
Claus Cursiefen,
Yuko Maruyama,
Nico van Rooijen,
Patricia A. D’Amore,
Shigeru Kinoshita
Publication year - 2012
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-8010
Subject(s) - lymphangiogenesis , lymphatic system , lymphatic vessel , lymphatic endothelium , cornea , pathology , integrin alpha m , transplantation , medicine , immune system , immunology , ophthalmology , surgery , cancer , metastasis
It has been shown previously that the presence in the cornea of antigen-presenting cells (APC), such as macrophages (MPS) and lymphangiogenesis, is a risk for corneal transplantation. We sought to determine whether the existence of lymphatic vessels in the non-inflamed cornea is associated with the presence of MPS.

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