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What Is Causing Active Trachoma? The Role of Nonchlamydial Bacterial Pathogens in a Low Prevalence Setting
Author(s) -
Matthew J. Burton,
Victor H. Hu,
Patrick Massae,
Sarah E. Burr,
Caroline Chevallier,
Isaac A. Afwamba,
Paul Courtright,
Helen A. Weiss,
David Mabey,
Robin L. Bailey
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.11-7326
Subject(s) - trachoma , chlamydia trachomatis , microbiology and biotechnology , chlamydia , biology , pathogen , streptococcus pneumoniae , haemophilus influenzae , chocolate agar , chlamydiaceae , haemophilus , agar plate , bacteria , immunology , medicine , antibiotics , genetics , pathology
In low prevalence settings, clinically active follicular trachoma (TF) is often found in the absence of detectable Chlamydia trachomatis. The reasons for this persistent follicular phenotype are not well understood; one possible explanation is that other bacterial species are provoking the inflammatory response. This study investigated the relationship between TF, C. trachomatis, and nonchlamydial bacterial infection.

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