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Analysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor Degeneration
Author(s) -
Matt Rutar,
Riccardo Natoli,
Peter Kozulin,
Krisztina Valter,
Paul A. Gatenby,
Jan Provis
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.10-7119
Subject(s) - complement system , microglia , in situ hybridization , retina , biology , retinal , pathology , gene expression , microbiology and biotechnology , complement receptor , tunel assay , retinal degeneration , immunohistochemistry , gene , immunology , inflammation , medicine , neuroscience , biochemistry , immune system
To investigate the expression and localization of complement system mRNA and protein in a light-induced model of progressive retinal degeneration.

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