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Preventive Effects of Ethyl Pyruvate on Endotoxin-Induced Uveitis in Rats
Author(s) -
Nilesh Kalariya,
Aramati B. M. Reddy,
Naseem H. Ansari,
Frederik J. G. M. VanKuijk,
Kota V. Ramana
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.10-7047
Subject(s) - chemokine , lipopolysaccharide , ciliary body , uveitis , inflammation , tumor necrosis factor alpha , cytokine , proinflammatory cytokine , nitric oxide , chemistry , nitric oxide synthase , endocrinology , immunology , pharmacology , medicine , pathology
Recent studies indicate that ethyl pyruvate (EP) exerts anti-inflammatory properties; however, the effect of EP on ocular inflammation is not known. The efficacy of EP in endotoxin-induced uveitis (EIU) in rats was investigated.

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