Preventive Effects of Ethyl Pyruvate on Endotoxin-Induced Uveitis in Rats
Author(s) -
Nilesh Kalariya,
Aramati B. M. Reddy,
Naseem H. Ansari,
Frederik J. G. M. VanKuijk,
Kota V. Ramana
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.10-7047
Subject(s) - chemokine , lipopolysaccharide , ciliary body , uveitis , inflammation , tumor necrosis factor alpha , cytokine , proinflammatory cytokine , nitric oxide , chemistry , nitric oxide synthase , endocrinology , immunology , pharmacology , medicine , pathology
Recent studies indicate that ethyl pyruvate (EP) exerts anti-inflammatory properties; however, the effect of EP on ocular inflammation is not known. The efficacy of EP in endotoxin-induced uveitis (EIU) in rats was investigated.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom