Effects of Subretinal Electrical Stimulation in Mer-KO Mice
Author(s) -
J. A. Mocko,
Moon Kim,
Amanda E. Faulkner,
Yang Cao,
Vincent T. Ciavatta,
Machelle T. Pardue
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.10-6750
Subject(s) - ciliary neurotrophic factor , glial fibrillary acidic protein , retinitis pigmentosa , electroretinography , erg , glial cell line derived neurotrophic factor , endocrinology , retinal , retinal degeneration , retina , medicine , neurotrophic factors , neuroprotection , biology , stimulation , neuroscience , immunohistochemistry , biochemistry , receptor
Subretinal electrical stimulation (SES) from microphotodiode arrays protects photoreceptors in the RCS rat model of retinitis pigmentosa. The authors examined whether mer(kd) mice, which share a Mertk mutation with RCS rats, showed similar neuroprotective effects from SES.
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