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Changes in Gene Expression in Human Meibomian Gland Dysfunction
Author(s) -
Shaohui Liu,
Stephen M. Richards,
Kristine Lo,
Mark P. Hatton,
Aaron Fay,
David A. Sullivan
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.10-6482
Subject(s) - meibomian gland , biology , gene , pathogenesis , gene expression , downregulation and upregulation , regulation of gene expression , pathology , endocrinology , eyelid , genetics , immunology , medicine , ophthalmology
Meibomian gland dysfunction (MGD) may be the leading cause of dry eye syndrome throughout the world. However, the precise mechanism(s) underlying the pathogenesis of this disease is unclear. This study was conducted to identify meibomian gland genes that may promote the development and/or progression of human MGD.

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