Open AccessTheBugeyeMutant Zebrafish Exhibits Visual Deficits that Arise with the Onset of an Enlarged Eye Phenotype
Author(s) -
Joseph M. Stujenske,
John E. Dowling,
Farida Emran
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.10-6434
Subject(s) - zebrafish , mutant , glaucoma , retinal , retina , biology , intraocular pressure , phenotype , retinal ganglion cell , electroretinography , ophthalmology , erg , genetics , medicine , neuroscience , gene , biochemistry
The bugeye mutant has an enlarged eye phenotype, presumably because of elevated intraocular pressure. Since elevated intraocular pressure is a significant risk factor for glaucoma, the bugeye zebrafish mutant may be a model organism for the disease.
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