Silicone Oil Microdroplets and Protein Aggregates in Repackaged Bevacizumab and Ranibizumab: Effects of Long-term Storage and Product Mishandling | Zendy

Lu Liu | Zendy; David A. Ammar | Zendy; Lindsey A. Ross | Zendy; Naresh Mandava | Zendy; Malik Y. Kahook | Zendy; John F. Carpenter | Zendy

Open Access

Silicone Oil Microdroplets and Protein Aggregates in Repackaged Bevacizumab and Ranibizumab: Effects of Long-term Storage and Product Mishandling

Author(s) -

Lu Liu,

David A. Ammar,

Lindsey A. Ross,

Naresh Mandava,

Malik Y. Kahook,

John F. Carpenter

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.10-6431

Subject(s) - bevacizumab , medicine , vial , silicone oil , compounding , chromatography , particle size , particle counter , ophthalmology , surgery , chemistry , materials science , pharmacology , aerosol , composite material , organic chemistry , chemotherapy

To quantify levels of subvisible particles and protein aggregates in repackaged bevacizumab obtained from compounding pharmacies, as well as in samples of bevacizumab and ranibizumab tested in controlled laboratory experiments.

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