Effect of Elevated Intracellular cAMP Levels on Actomyosin Contraction in Bovine Trabecular Meshwork Cells | Zendy

Charanya Ramachandran | Zendy; Rajkumar V. Patil | Zendy; Najam A. Sharif | Zendy; Sangly P. Srinivas | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effect of Elevated Intracellular cAMP Levels on Actomyosin Contraction in Bovine Trabecular Meshwork Cells

Author(s) -

Charanya Ramachandran,

Rajkumar V. Patil,

Najam A. Sharif,

Sangly P. Srinivas

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.10-6241

Subject(s) - rhoa , forskolin , phosphorylation , rho associated protein kinase , myosin light chain kinase , trabecular meshwork , microbiology and biotechnology , myosin light chain phosphatase , chemistry , protein kinase a , signal transduction , biology , biochemistry , in vitro , neuroscience , glaucoma

Elevated cAMP in the trabecular meshwork (TM) cells increases the aqueous humor outflow facility. The authors investigated the mechanisms by which elevated cAMP opposes the RhoA-Rho kinase pathway, leading to the relaxation of the actomyosin system in bovine TM cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research