Open AccessComputational Quantification of Complex Fundus Phenotypes in Age-Related Macular Degeneration and Stargardt Disease
Author(s) -
Gwénolé Quellec,
Stephen R. Russell,
Todd E. Scheetz,
Edwin M. Stone,
Michael D. Abràmoff
Publication year - 2011
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.10-6232
Subject(s) - drusen , macular degeneration , fundus (uterus) , stargardt disease , abca4 , ophthalmology , medicine , phenotype , receiver operating characteristic , pathology , biology , genetics , gene
To describe an automated method of quantification of specific fundus phenotypes and evaluate its performance in differentiating drusen, the hallmark lesions of age-related macular degeneration (AMD), from similar-looking bright lesions, the pisciform deposits or flecks typical of Stargardt disease (SD).