Regulation of Corneal Epithelial Barrier Function by Krüppel-like Transcription Factor 4 | Zendy

Sudha Swamynathan | Zendy; Doreswamy Kenchegowda | Zendy; Joram Piatigorsky | Zendy; Shivalingappa K. Swamynathan | Zendy

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Regulation of Corneal Epithelial Barrier Function by Krüppel-like Transcription Factor 4

Author(s) -

Sudha Swamynathan,

Doreswamy Kenchegowda,

Joram Piatigorsky,

Shivalingappa K. Swamynathan

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.10-6134

Subject(s) - hemidesmosome , klf4 , barrier function , microbiology and biotechnology , basement membrane , corneal epithelium , adherens junction , biology , tight junction , cornea , transcription factor , chemistry , cell , cadherin , biochemistry , sox2 , neuroscience , gene

Previously, the authors showed that Klf4-conditional null (Klf4CN) corneas display epithelial fragility. Here, they investigated the mechanism by which Klf4 regulates corneal epithelial barrier function.

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