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Factors Impacting Corneal Epithelial Barrier Function againstPseudomonas aeruginosaTraversal
Author(s) -
I. Alarcon,
Connie Tam,
James J. Mun,
Jeffrey LeDue,
David J. Evans,
Suzanne M. J. Fleiszig
Publication year - 2010
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.10-6125
Subject(s) - cornea , fluorescein , blot , corneal epithelium , ex vivo , staining , biology , epithelium , in vivo , microbiology and biotechnology , pseudomonas aeruginosa , pathology , chemistry , in vitro , bacteria , biochemistry , fluorescence , medicine , genetics , neuroscience , physics , quantum mechanics , gene
Mechanisms determining epithelial resistance versus susceptibility to microbial traversal in vivo remain poorly understood. Here, a novel murine model was used to explore factors influencing the corneal epithelial barrier to Pseudomonas aeruginosa penetration.

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