XIAP Therapy Increases Survival of Transplanted Rod Precursors in a Degenerating Host Retina | Zendy

Jingyu Yao | Zendy; Kecia L. Feathers | Zendy; Hemant Khanna | Zendy; Debra A. Thompson | Zendy; Catherine Tsilfidis | Zendy; William W. Hauswirth | Zendy; John R. Heckenlively | Zendy; Anand Swaroop | Zendy; David N. Zacks | Zendy

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XIAP Therapy Increases Survival of Transplanted Rod Precursors in a Degenerating Host Retina

Author(s) -

Jingyu Yao,

Kecia L. Feathers,

Hemant Khanna,

Debra A. Thompson,

Catherine Tsilfidis,

William W. Hauswirth,

John R. Heckenlively,

Anand Swaroop,

David N. Zacks

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.10-5998

Subject(s) - xiap , transplantation , retina , retinal , outer nuclear layer , biology , photoreceptor cell , retinal degeneration , muller glia , apoptosis , microbiology and biotechnology , programmed cell death , cancer research , immunology , stem cell , medicine , neuroscience , caspase , progenitor cell , biochemistry

To assess the survival of rod precursor cells transplanted into the Rd9 mouse, a model of X-linked retinal degeneration, and the effect of antiapoptotic therapy with X-linked inhibitor of apoptosis (XIAP) on preventing cell loss.

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