Claudin-19 and the Barrier Properties of the Human Retinal Pigment Epithelium | Zendy

Shaomin Peng | Zendy; Veena Rao | Zendy; Ron A. Adelman | Zendy; Lawrence J. Rizzolo | Zendy

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Claudin-19 and the Barrier Properties of the Human Retinal Pigment Epithelium

Author(s) -

Shaomin Peng,

Veena Rao,

Ron A. Adelman,

Lawrence J. Rizzolo

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.10-5984

Subject(s) - occludin , claudin , tight junction , retinal pigment epithelium , paracellular transport , retinal , epithelium , retina , blood–retinal barrier , microbiology and biotechnology , chemistry , small interfering rna , gene knockdown , biology , permeability (electromagnetism) , cell culture , endocrinology , transfection , biochemistry , genetics , neuroscience , membrane , diabetic retinopathy , diabetes mellitus

The retinal pigment epithelium (RPE) separates photoreceptors from choroidal capillaries, but in age-related macular degeneration (AMD) capillaries breach the RPE barrier. Little is known about human RPE tight junctions or the effects of serum on the retinal side of the RPE.

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