Culture, Immortalization, and Characterization of Human Meibomian Gland Epithelial Cells | Zendy

Shaohui Liu | Zendy; Mark P. Hatton | Zendy; Payal Khandelwal | Zendy; David A. Sullivan | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Culture, Immortalization, and Characterization of Human Meibomian Gland Epithelial Cells

Author(s) -

Shaohui Liu,

Mark P. Hatton,

Payal Khandelwal,

David A. Sullivan

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.09-5108

Subject(s) - meibomian gland , telomerase reverse transcriptase , immortalised cell line , biology , cell culture , telomerase , epithelium , cell , microbiology and biotechnology , gene , biochemistry , medicine , genetics , surgery , eyelid

Meibomian gland epithelial cells are essential in maintaining the health and integrity of the ocular surface. However, very little is known about their physiological regulation. In this study, the cellular control mechanisms were explored, first to establish a defined culture system for the maintenance of primary epithelial cells from human meibomian glands and, second, to immortalize these cells, thereby developing a preclinical model that could be used to identify factors that regulate cell activity.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research