Incomplete Cortical Reorganization in Macular Degeneration | Zendy

Tingting Liu | Zendy; Sing-Hang Cheung | Zendy; Ronald Schuchard | Zendy; Christopher Glielmi | Zendy; Xiaoping Hu | Zendy; Sheng He | Zendy; Gordon E. Legge | Zendy

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Incomplete Cortical Reorganization in Macular Degeneration

Author(s) -

Tingting Liu,

Sing-Hang Cheung,

Ronald Schuchard,

Christopher Glielmi,

Xiaoping Hu,

Sheng He,

Gordon E. Legge

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.09-4926

Subject(s) - stimulus (psychology) , functional magnetic resonance imaging , neuroscience , visual cortex , psychology , macular degeneration , foveal , occipital lobe , fovea centralis , retina , brain mapping , retinal , medicine , ophthalmology , cognitive psychology , psychiatry

Activity in regions of the visual cortex corresponding to central scotomas in subjects with macular degeneration (MD) is considered evidence for functional reorganization in the brain. Three unresolved issues related to cortical activity in subjects with MD were addressed: Is the cortical response to stimuli presented to the preferred retinal locus (PRL) different from other retinal loci at the same eccentricity? What effect does the role of age of onset and etiology of MD have on cortical responses? How do functional responses in an MD subject's visual cortex vary for task and stimulus conditions?

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