VIP Promotes Resistance in thePseudomonas aeruginosa–Infected Cornea by Modulating Adhesion Molecule Expression | Zendy

Elizabeth A. Berger | Zendy; Sharon A. McClellan | Zendy; Ronald P. Barrett | Zendy; Linda D. Hazlett | Zendy

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VIP Promotes Resistance in thePseudomonas aeruginosa–Infected Cornea by Modulating Adhesion Molecule Expression

Author(s) -

Elizabeth A. Berger,

Sharon A. McClellan,

Ronald P. Barrett,

Linda D. Hazlett

Publication year - 2010

Publication title -

investigative ophthalmology and visual science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.935

H-Index - 218

eISSN - 1552-5783

pISSN - 0146-0404

DOI - 10.1167/iovs.09-4917

Subject(s) - cell adhesion molecule , intercellular adhesion molecule 1 , microbiology and biotechnology , cell adhesion , vasoactive intestinal peptide , vcam 1 , intercellular adhesion molecule , cornea , biology , icam 1 , chemistry , immunology , cell , biochemistry , neuropeptide , receptor , neuroscience

This study tested the hypothesis that the neuropeptide vasoactive intestinal peptide (VIP) regulates adhesion molecule expression, reduces inflammatory cell migration and infiltration into the Pseudomonas aeruginosa-infected cornea of susceptible B6 mice, and promotes corneal healing and resistance.

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