Restricted Localization of Ponli, a Novel Zebrafish MAGUK-Family Protein, to the Inner Segment Interface Areas between Green, Red, and Blue Cones
Author(s) -
Jian Zou,
Xiaojun Yang,
Xiangyun Wei
Publication year - 2010
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.09-4520
Subject(s) - zebrafish , biology , anatomy , microbiology and biotechnology , genetics , gene
The inner segments (IS) of the photoreceptors in vertebrates are enriched with polarity scaffold proteins, which maintain the integrity of many tissues by mediating cell-cell adhesion either directly or indirectly. The formation of photoreceptor mosaics may require differential adhesion among different types of photoreceptors. It is unknown whether any polarity proteins are selectively expressed in certain photoreceptors to mediate differential intercellular adhesion, which may be important for photoreceptor patterning. This study was undertaken to identify such polarity proteins.
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