Open AccessDependence of Resolvin-Induced Increases in Corneal Epithelial Cell Migration on EGF Receptor Transactivation
Author(s) -
Fan Zhang,
Hua Yang,
Zhongdang Pan,
Zheng Wang,
J. Mario Wolosin,
P. Gjörstrup,
Peter S. Reinach
Publication year - 2010
Publication title -
investigative ophthalmology and visual science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.935
H-Index - 218
eISSN - 1552-5783
pISSN - 0146-0404
DOI - 10.1167/iovs.09-4468
Subject(s) - wortmannin , phosphorylation , microbiology and biotechnology , protein kinase b , ly294002 , cell migration , transactivation , chemistry , signal transduction , biology , cell , biochemistry , transcription factor , gene
To determine whether resolvin E1 (RvE1), an endogenous oxygenation product of eicosapentaenoic acid (EPA), induces increases in migration in human corneal epithelial cells (HCECs) and to identify signal pathways mediating this response.